Overview

Original Research

LEAD IDENTIFICATION AGAINST MULTI DRUG RESISTANT ESKAPE PATHOGENS ON E. FAECIUM USING INHOUSE HERBAL MEDICINAL DATABASE

V V ANIERUDHE 1, and K SREEVANI 2.

Vol 17, No 10 ( 2022 )   |  DOI: 10.5281/zenodo.7302488   |   Author Affiliation: Department of Biotechnology, B S Abdur Rahman Crescent Institute of Science & Technology, Vandalur, Chennai 1; Department of Physics, Panimalar College of Engineering (City campus), Nungampakkam, Chennai 2.   |   Licensing: CC 4.0   |   Pg no: 2331-2347   |   To cite: V V ANIERUDHE, and K SREEVANI. (2022). LEAD IDENTIFICATION AGAINST MULTI DRUG RESISTANT ESKAPE PATHOGENS ON E. FAECIUM USING INHOUSE HERBAL MEDICINAL DATABASE. 17(10), 2331–2347. https://doi.org/10.5281/zenodo.7302488   |   Published on: 31-10-2022

Abstract

Colorectal cancer or Colon cancer is the third most common cancer in the Western hemisphere and the incidence increases with the age. Most Colorectal cancers are localized with or without lymph node metastases where up to 20% of the patients present with metastatic disease, most commonly to the liver. Surgery is the only remedial therapy for localized colorectal cancer. The 5EYF Protein molecule of Enterococcus faecium is targeted with 1000 ligand molecules of herbal compounds and after that ADME prediction is done. The aim of the present work is to provide an overview of medicinal plants compounds on colon cancer using Enterococcus faecium and find a therapeutic drug using 5EYF protein molecule.

Keywords

Colon Cancer, Enterococcus faecium, Autodock Vina, Pymol.