THE WOUND HEALING AND ANTIMICROBIAL ACTIVITY OF CARABAO HORN (CORNU BUBALI) CREAM
The study was conducted to alleviate the problems in slaughterhouse wastes and promote the utilization of alternative cures for wounds in the absence of commercial ones. The present investigation reveals the wound-healing and antibacterial nature of carabao horn and these result justifies the folkloric claim of the community. The study aimed to determine if there was a significant difference between the four treatments in terms of wound size and determine its antimcorbial activity. The study was conducted to establish the scientific basis for the utilization of carabao horn as wound medicine. There were four treatments of the study and were tested using 12 male albino mice, comprising 3 mice per group. The experimented albino mice were firstly acclimatized to laboratory conditions for 5 days before the start of the experiment. The treatments were topically applied to the wound of the mice until healed. Results of the study revealed that Treatment 1 has the highest percentage of wound closure (HPWC) 83% higher than the positive control, erythromycin with 64% HPWC. The wound sizes in the animals treated with the positive control, erythromycin showed by the 17th day, indicating that treatment 1, at that given concentration, had a better wound healing property than the positive control. Result of the antimicrobial activity of the carabao horn cream showed that the cream was partially active against Staphyloccus aureus and Escherichia coli and inhibited greater ZOI (zone of inhibition) than the positive control. The antimicrobial property of the carabao horn investigated aids in the wound healing promotion of the sample excuted among the test specimens. The study further suggests looking into the Physico-chemical properties and other microbiological activities of the carabao horn.
Natural Product, Waste Utilization, and Wound-Healing Activity